A salt-and alkali-resistant star-polymer was made using graft β-CD functional monomer and acrylamide monomer employing copolymerization and post-hydrolysis methods. The optimum parameters: azobisisobutyronitrile with a concentration of 50 mg/L, a mass fraction of acrylamide 25%, a graft β-CD functional monomer mass fraction of 1.5%, initiating temperature 5 °C, hydrolysis temperature 90 °C and hydrolysis time of 3 hours. The atomic force microscope and infrared spectroscopy morphology characterization results show that: the star-polymer S07313 contains the star-nucleu of the graft β-CD functional monomer. The molecular weight of the star-polymer S07313 is 24.5 million, while other basic physical and chemical properties can meet the technical requirements of the application of such a polymer in oil fields. With the addition of NaOH as a mass fraction of 1.0% in the Daqing simulated brine, the apparent viscosities of the star-polymer S07313, HPAM3000 and MO4000 are 42.40 mPa·s, 29.20 mPa·s and 18.00 mPa·s. The star-polymer S07313 and surface active agents Alkylbenzene Sulfonate have an excellent compatibility